A study performed by vaccine manufacturer Vanguard using a COMBINATION vaccine (one which contains several different vaccines) tested the efficiency of the vaccine in stimulating antibodies in an immune response.
This is what they found:
- When vaccinated at 6 weeks old, 52% of puppies showed an adequate immune response
- When vaccinated at 9 weeks old, 88% of puppies showed an adequate immune response
- When vaccinated at 12 weeks old, 100% of puppies showed an adequate immune response
According to the World Small Animal Veterinary Association (WSVA) Vaccination Guidelines, individual puppies may absorb more, or less, of the antibodies from colostrum than their siblings.
This could result in one puppy responding to vaccination earlier/later than another… even in the same litter. It’s not an exact science. Yet.
And that’s not all.
Researchers at Purdue University, Indiana, found that the risk of side effects associated increased dramatically with each round of vaccinations:
- For smaller dogs, under 22lbs, the risk of adverse vaccine reactions increased by 27% each time
- For medium to large dogs, over 22lbs, the risk showed a 12% increase.
Yup, there’s more.
In 1996, Pfizer Pharmaceutical Company performed a study to measure the immune response of puppies to a SINGLE vaccine.
The puppies were divided into two groups.
One group were vaccinated twice, once between 8 and 10 weeks of age, and once at 12 weeks.
The second group was vaccinated once, at 12 weeks of age.
After the 12 weeks shots, both groups were tested for antibody levels and immune response.
Guess which group responded better? Yes, the puppies who were vaccinated just once!
The results of the study showed:
- 98% of the puppies vaccinated twice showed adequate immune response
- 100% of the puppies vaccinated once showed an adequate immune response
The above information is an excerpt from https://peterdobias.com/blogs/blog/safer-vaccination-in-adult-dogs-and-puppies
Some more information may be found here: